Job Description

Job Title:  Research Associate, Analytical Development

Department:  Research and Development

Location:  Rochester, Minnesota

Rion is a clinical-stage biotechnology company based in Rochester, Minnesota, founded as a Mayo Clinic Employee Entrepreneurial Program startup company. Rion’s mission is to develop clinically impactful and accessible therapies using innovative regenerative medicine technologies based on extracellular vesicle science. Our proprietary exosome platform has the ability to address significant unmet patient needs in many fields of medicine. We are actively pursuing clinical programs in wound healing, cardiovascular disease, and musculoskeletal diseases. Our ultimate mission is to deliver cutting edge solutions accessible to any patient in need, anywhere in the world.

Position Summary:

The Analytical Development Research Associate will contribute to analytical method development, implementation, and pre-qualification of methods focused on Rion’s exosome technology. This role will work closely with Rion Quality Control to execute method transfers and support continuous improvement. As such, the candidate will possess the technical skills required to conduct experiments and assays in a wet lab environment involving techniques such as mammalian cell culture, ELISA, RT-qPCR, HPLC and colorimetric/fluorometric-based assays. The Analytical Development Research Associate will be responsible for the execution of experiments, as well as data interpretation and final reporting. The position affords the opportunity to serve as a key member of Rion’s scientific team and contribute to the advancement of exosome therapeutics. The Analytical Development Research Associate will work closely with the Analytical Development Scientists and support the efforts of Quality Control/Process Development. As such, the successful candidate will work in an upbeat, highly collaborative and dynamic environment. Additional responsibilities associated with this position will involve assisting in day-to-day laboratory operations such as inventory management, procurement, and general laboratory and equipment maintenance.

Responsibilities:

• Contribute to ongoing scientific studies centered on Rion’s exosome technology
• Execute experiments in a wet lab setting
• Generate summary reports and/or presentations to communicate findings to the Rion Research and Development/Quality Control/Process Development teams
• Maintain regulatory compliance appropriate for study execution, including all prescribed training as found in SOPs and work instructions
• Willingness to learn and understand GLP guidance for execution of studies
• Utilize a paper-based laboratory notebook to document daily activities and maintain an organized index of experiments and results
• Demonstrate leadership skills and support peers in a collaborative environment
• Independently analyze experimental data and provide conclusive insights
• Remain up to date with current scientific literature with an emphasis on extracellular vesicle therapeutics and indications
• Prepare technical reports, review data as second analyst for the validations, and evaluate new instrumentation and analytical techniques as required

· Perform analytical testing (e.g. protein expression, bioassays, and particle analysis, cell-based assays)

Minimum Qualifications:

• Bachelor’s or Master’s degree with focus in Biological Sciences
• 1+ years of relevant work experience or analytical development experience in a biological sciences laboratory
• Prior experience in research laboratory with demonstrated ability to summarize findings and compose technical scientific documents. Experience with mammalian cell culture, ELISA, RT-qPCR and/or HPLC
• Sound scientific knowledge in cellular biology and human disease
• Proficient in data analysis and graphical software (ex. Microsoft Excel, GraphPad Prism)
• Excellent communication skills and ability to present findings
• Strong organizational and time management skills
• Ability to solve problems and work independently
• Demonstrated ability to work as a team player with multi-disciplinary project teams

· Experience working in an analytical development environment is a plus

Rion recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue career path their goals, both at work and in their personal lives.

We provide a highly competitive compensation package with a unique culture focusing on development and wellbeing of our staff. Below are some of the benefits offered by Rion:

· Comprehensive benefits package

· Health Insurance including PPO or High Deductible Health Plan with Health Savings Account

· Dental Insurance

· Vision Insurance

· Flexible Spending Accounts (FSA)

· 401K Retirement Savings

· Life Insurance basic life and supplemental life insurance options for self, spouse, children

· Short and Long-Term Disability Insurance

· Discretionary Time-off, Paid Holidays, and Parental Leave programs

· Parking benefits

Rion is an equal opportunity employer and complies with all applicable federal, state and local fair employment practices laws. Rion strictly prohibits and does not tolerate discrimination against employees, applicants or any other covered persons because of race, color, religion, creed, national origin or ancestry, ethnicity, sex (including pregnancy), gender (including gender nonconformity and status as a transgender or transsexual individual), age, physical or mental disability, citizenship, past, current or prospective service in the uniformed services, genetic information, marital status, AIDS/HIV status, smoker/nonsmoker, and occupational pneumoconiosis or any other characteristic protected under applicable federal, state or local law.

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